The Liver and Its Functions (2024)

The liver is the largest solid organ in the body. It removes toxins from the body’s blood supply, maintains healthy blood sugar levels, regulates blood clotting, and performs hundreds of other vital functions. It is located beneath the rib cage in the right upper abdomen.

Key Facts

  • The liver filters all of the blood in the body and breaks down poisonous substances, such as alcohol and drugs.
  • The liver also produces bile, a fluid that helps digest fats and carry away waste.
  • The liver consists of four lobes, which are each made up of eight sections and thousands of lobules (or small lobes).

Functions of the Liver

The liver is an essential organ of the body that performs over 500 vital functions. These include removing waste products and foreign substances from the bloodstream, regulating blood sugar levels, and creating essential nutrients. Here are some of its most important functions:

  • Albumin Production: Albumin is a protein that keeps fluids in the bloodstream from leaking into surrounding tissue. It also carries hormones, vitamins, and enzymes through the body.
  • Bile Production: Bile is a fluid that is critical to the digestion and absorption of fats in the small intestine.
  • Filters Blood: All the blood leaving the stomach and intestines passes through the liver, which removes toxins, byproducts, and other harmful substances.
  • Regulates Amino Acids: The production of proteins depend on amino acids. The liver makes sure amino acid levels in the bloodstream remain healthy.
  • Regulates Blood Clotting: Blood clotting coagulants are created using vitamin K, which can only be absorbed with the help of bile, a fluid the liver produces.
  • Resists Infections: As part of the filtering process, the liver also removes bacteria from the bloodstream.
  • Stores Vitamins and Minerals: The liver stores significant amounts of vitamins A, D, E, K, and B12, as well as iron and copper.
  • Processes Glucose: The liver removes excess glucose (sugar) from the bloodstream and stores it as glycogen. As needed, it can convert glycogen back into glucose.

Anatomy of the Liver

The liver is reddish-brown and shaped approximately like a cone or a wedge, with the small end above the spleen and stomach and the large end above the small intestine. The entire organ is located below the lungs in the right upper abdomen. It weighs between 3 and 3.5 pounds.

The Liver and Its Functions (1)

Structure

The liver consists of four lobes: the larger right lobe and left lobe, and the smaller caudate lobe and quadrate lobe. The left and right lobe are divided by the falciform (“sickle-shaped” in Latin) ligament, which connects the liver to the abdominal wall. The liver’s lobes can be further divided into eight segments, which are made up of thousands of lobules (small lobes). Each of these lobules has a duct flowing toward the common hepatic duct, which drains bile from the liver.

Parts

The following are some of the most important individual parts of the liver:

  • Common Hepatic Duct: A tube that carries bile out of the liver. It is formed from the intersection of the right and left hepatic ducts.
  • Falciform Ligament: A thin, fibrous ligament that separates the two lobes of the liver and connects it to the abdominal wall.
  • Glisson’s Capsule: A layer of loose connective tissue that surrounds the liver and its related arteries and ducts.
  • Hepatic Artery: The main blood vessel that supplies the liver with oxygenated blood.
  • Hepatic Portal Vein: The blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas, and spleen to the liver.
  • Lobes: The anatomical sections of the liver.
  • Lobules: Microscopic building blocks of the liver.
  • Peritoneum: A membrane covering the liver that forms the exterior.

Maintaining a Healthy Liver

The best way to avoid liver disease is to take active steps toward a healthy life. The following are some recommendations that will help keep the liver functioning as it should:

  • Avoid Illicit Drugs: Illicit drugs are toxins that the liver must filter out. Taking these drugs can cause long-term damage.
  • Drink Alcohol Moderately: Alcohol must be broken down by the liver. While the liver can moderate amounts, excessive alcohol use can cause damage.
  • Exercise Regularly: A regular exercise routine will help promote general health for every organ, including the liver.
  • Eat Healthy Foods: Eating excessive fats can make it difficult for the liver to function and lead to fatty liver disease.
  • Practice Safe Sex: Use protection to avoid sexually transmitted diseases such as hepatitis C.
  • Vaccinate: Especially when traveling, get appropriate vaccinations against hepatitis A and B, as well as diseases such as malaria and yellow fever, which grow in the liver.

Next Steps

If you need help for a liver condition, give us a call at (877) LIVER MD/ (877) 548-3763 or get in touch using our online request form.

The Liver and Its Functions (2024)

FAQs

The Liver and Its Functions? ›

The liver is the storage location for fat-soluble vitamins and handles cholesterol homeostasis. It stores iron and copper. It plays a role in hematology with clotting factors and protein synthesis. The liver plays a role in heme breakdown into unconjugated bilirubin and conjugates it.

How do you know your liver is unhealthy? ›

Early symptoms
  • generally feeling unwell and tired all the time.
  • loss of appetite.
  • loss of weight and muscle wasting.
  • feeling sick (nausea) and vomiting.
  • tenderness/pain in the liver area.
  • spider-like small blood capillaries on the skin above waist level (spider angiomas)
  • blotchy red palms.
  • disturbed sleep patterns.

What are the 5 functions of the liver in digestion? ›

The Digestive Process: The Liver and its Many Functions
  • Producing important substances. Your liver continually produces bile. ...
  • Processing bilirubin. The liver helps your body get rid of bilirubin. ...
  • Removing waste products. ...
  • Controls immune responses. ...
  • Controlling glucose.

How to get a stronger liver? ›

Heed these tips to stay right with your liver.
  1. Be careful about alcohol consumption. If you think only lifelong, falling-down drunks get cirrhosis of the liver — you're mistaken. ...
  2. Wash produce and steer clear of toxins. ...
  3. Prevent hepatitis A, B and C. ...
  4. Watch out for medications and herbs. ...
  5. Exercise and eat right.

Where do you feel liver pain? ›

Liver pain is typically felt in the upper right abdomen beneath the rib cage. It can also radiate to the back and shoulder. Consulting a healthcare professional is crucial for accurate diagnosis and treatment.

What are the three worst things for your liver? ›

What foods are bad for your liver?
  1. Fast food. It's quick, it's cheap, and sometimes you really crave it. ...
  2. Ultra-processed foods. ...
  3. Sweetened foods. ...
  4. Sugary drinks. ...
  5. Artificial sweeteners. ...
  6. Refined grains. ...
  7. Red meat and processed meats. ...
  8. Alcohol.
Apr 1, 2024

How do you detoxify your liver? ›

What foods help detoxify the liver? Some great foods to help cleanse and support liver function include leafy greens like spinach and kale, avocados, broccoli, cauliflower, garlic, grapefruit, green tea, turmeric, apples, olive oil, citrus fruits, beets, and cruciferous vegetables like Brussels sprouts and cabbage.

What heals the liver fast? ›

Top foods and drinks for liver health
  • Coffee. A 2021 study analyzed data from 494,585 people in the United Kingdom to learn how different types of coffee might affect the risk of chronic liver disease, including decaffeinated, instant, and ground coffee. ...
  • Oatmeal. ...
  • Green tea. ...
  • Garlic. ...
  • Berries. ...
  • Grapes. ...
  • Grapefruit. ...
  • Prickly pear.

What is the number one food for your liver? ›

In general, a diet high in whole, nutrient-dense foods, like fruits, vegetables, legumes, and seafood, and low in ultra-processed food, alcohol, and added sugar is what's best for liver health.

What is the super food for the liver? ›

Here are some foods that are good choices for your liver
  • Lean proteins. Getting enough protein is crucial for your liver, and lean chicken, turkey, fish and beef are good options. ...
  • Fruits and vegetables. ...
  • Olive oil. ...
  • Nuts and seeds. ...
  • Oatmeal. ...
  • Coffee and tea.
Mar 3, 2023

What are the symptoms of a weak liver? ›

If there are symptoms of liver disease, they may include:
  • Yellowing of the skin and the whites of the eyes, called jaundice. ...
  • Belly pain and swelling.
  • Swelling in the legs and ankles.
  • Itchy skin.
  • Dark urine.
  • Pale stool.
  • Constant tiredness.
  • Nausea or vomiting.
Feb 13, 2024

What side is your liver on female? ›

The liver is located in the upper right-hand portion of the abdominal cavity, beneath the diaphragm, and on top of the stomach, right kidney, and intestines.

What side is your pancreas on? ›

The pancreas is located behind the stomach in the upper left abdomen. It is surrounded by other organs including the small intestine, liver, and spleen.

What is the most important liver function? ›

The liver regulates most chemical levels in the blood and excretes a product called bile. This helps carry away waste products from the liver. All the blood leaving the stomach and intestines passes through the liver.

Is your liver on the left or right side? ›

The liver is an organ located in the upper right part of the belly (abdomen). It is beneath the diaphragm and on top of the stomach, right kidney, and intestines. The liver has many functions.

Where does bile go after the liver? ›

The liver cells secrete the bile into small canals that lead to the common bile duct. From there, a smaller duct branches off and leads to the gallbladder. The common bile duct ends at the small intestine. The bile produced by the liver flows directly into the small intestine during a meal.

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